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; Cekan, S. Patients with malignant small intestinal tumors generally present with advanced disease because of the vague [19] TABLE 25-4 -- Incidence and Distribution of Malignant Tumors of the Small Intestine Type of Tumor Duodenum () Jejunum () Ileum () Overall () Adenocarcinoma 3544 3040 2025 4555 Carcinoid tumor 1020 3040 4050 2030 Lymphoma 115 510 7585 2030 Leiomyosarcoma (GIST) 19 4050 5060 1015 V-360 TABLE 25-5 -- Clinical Presentation of Small Bowel Neoplasms more distal mutations will bind and inactivate a normal APC protein and result in aggressive forms of the disease.

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